Stadium: Jack Breslin Students Events Center Round: 1
Home Manager: Tom Izzo Away Manager: Fran McCaffery
| NCAAB | 2019/01/25 00:00 | Michigan State v Iowa | L | 82-67 |
| NCAAB | 2018/12/03 23:30 | Iowa v Michigan State | L | 68-90 |
| NCAAB | 2018/02/07 02:00 | Michigan State v Iowa | L | 96-93 |
| NCAAB | 2017/02/11 23:00 | Iowa v Michigan State | L | 66-77 |
| NCAAB | 2016/01/15 00:00 | Michigan State v Iowa | W | 59-76 |
| NCAAB | 2015/12/30 02:00 | Iowa v Michigan State | W | 83-70 |
| NCAAB | 2015/01/09 00:00 | Iowa v Michigan State | L | 61-75 |
| NCAAB | 2014/03/06 12:00 | Michigan State v Iowa | L | 86-76 |
| NCAAB | 2012/03/09 12:00 | Michigan State v Iowa | L | 92-75 |
| NCAAB | 2012/01/10 12:00 | Michigan State v Iowa | L | 95-61 |
| NCAAB | 2011/03/10 12:00 | Michigan State v Iowa | L | 66-61 |
| NCAAB | 2011/03/02 12:00 | Michigan State v Iowa | L | 85-66 |
| NCAAB | 2011/02/02 12:00 | Iowa v Michigan State | W | 72-52 |
| NCAAB | 2010/01/20 12:00 | Michigan State v Iowa | L | 70-63 |
| NCAAB | 2010/01/09 12:00 | Iowa v Michigan State | L | 53-71 |
| NCAAB | 2009/02/25 12:00 | Michigan State v Iowa | L | 62-54 |
| NCAAB | 2009/01/29 12:00 | Iowa v Michigan State | L | 56-71 |
| NCAAB | 2008/02/23 12:00 | Michigan State v Iowa | L | 66-52 |
| NCAAB | 2008/01/12 12:00 | Iowa v Michigan State | W | 43-36 |
| NCAAB | 2007/02/17 12:00 | Michigan State v Iowa | L | 81-49 |
| NCAAB | 2007/01/04 12:00 | Iowa v Michigan State | W | 62-60 |
| NCAAB | 2006/03/11 12:00 | Iowa v Michigan State | W | 53-48 |
| NCAAB | 2006/02/14 12:00 | Iowa v Michigan State | W | 66-54 |
| NCAAB | 2006/01/21 12:00 | Michigan State v Iowa | L | 85-55 |
| NCAAB | 2005/03/11 12:00 | Iowa v Michigan State | W | 71-69 |
| NCAAB | 2005/02/05 12:00 | Iowa v Michigan State | L | 64-75 |
| NCAAB | 2004/02/04 12:00 | Michigan State v Iowa | L | 89-72 |
| NCAAB | 2003/03/05 12:00 | Michigan State v Iowa | L | 82-54 |
| NCAAB | 2003/01/11 12:00 | Iowa v Michigan State | W | 68-64 |