Stadium: Jack Breslin Students Events Center Round: 1
Home Manager: Tom Izzo Away Manager: Pat Chambers
| NCAAB | 2019/01/13 21:30 | Michigan State v Penn State | L | 71-56 |
| NCAAB | 2018/01/31 23:30 | Penn State v Michigan State | L | 68-76 |
| NCAAB | 2017/03/09 19:40 | Penn State v Michigan State | L | 51-78 |
| NCAAB | 2017/01/07 18:00 | Michigan State v Penn State | W | 63-72 |
| NCAAB | 2016/02/28 17:00 | Michigan State v Penn State | L | 88-57 |
| NCAAB | 2016/01/10 17:00 | Penn State v Michigan State | L | 65-92 |
| NCAAB | 2015/01/22 00:00 | Michigan State v Penn State | L | 66-60 |
| NCAAB | 2012/02/08 12:00 | Michigan State v Penn State | L | 77-57 |
| NCAAB | 2011/03/12 12:00 | Penn State v Michigan State | W | 61-48 |
| NCAAB | 2011/02/10 12:00 | Michigan State v Penn State | L | 75-57 |
| NCAAB | 2011/01/08 12:00 | Penn State v Michigan State | W | 66-62 |
| NCAAB | 2010/03/04 12:00 | Michigan State v Penn State | L | 67-65 |
| NCAAB | 2010/02/13 12:00 | Penn State v Michigan State | L | 54-65 |
| NCAAB | 2009/02/01 12:00 | Michigan State v Penn State | W | 68-72 |
| NCAAB | 2009/01/14 12:00 | Penn State v Michigan State | L | 73-78 |
| NCAAB | 2008/02/20 12:00 | Michigan State v Penn State | L | 86-49 |
| NCAAB | 2008/02/02 12:00 | Penn State v Michigan State | W | 85-76 |
| NCAAB | 2007/01/20 12:00 | Penn State v Michigan State | L | 64-91 |
| NCAAB | 2006/01/28 12:00 | Michigan State v Penn State | L | 69-60 |
| NCAAB | 2005/03/05 12:00 | Michigan State v Penn State | L | 90-64 |
| NCAAB | 2005/01/05 12:00 | Penn State v Michigan State | L | 58-84 |
| NCAAB | 2004/02/28 12:00 | Penn State v Michigan State | L | 42-67 |
| NCAAB | 2004/01/14 12:00 | Michigan State v Penn State | L | 76-58 |
| NCAAB | 2003/01/22 12:00 | Michigan State v Penn State | L | 70-36 |