Stadium: Redbird Arena Round: 1
Home Manager: Dan Muller Away Manager: Bryan Mullins
| NCAAB | 2020/01/04 21:00 | Illinois St v Southern Illinois | W | 55-67 |
| NCAAB | 2019/03/02 19:00 | Illinois St v Southern Illinois | W | 63-72 |
| NCAAB | 2019/01/16 00:00 | Southern Illinois v Illinois St | L | 58-59 |
| NCAAB | 2018/03/04 00:10 | Illinois St v Southern Illinois | L | 76-68 |
| NCAAB | 2018/02/09 02:00 | Southern Illinois v Illinois St | L | 68-76 |
| NCAAB | 2018/01/13 23:00 | Illinois St v Southern Illinois | W | 70-74 |
| NCAAB | 2017/03/04 20:30 | Southern Illinois v Illinois St | L | 50-63 |
| NCAAB | 2017/02/23 00:00 | Illinois St v Southern Illinois | L | 50-46 |
| NCAAB | 2017/01/12 01:00 | Southern Illinois v Illinois St | L | 53-60 |
| NCAAB | 2016/02/25 00:00 | Illinois St v Southern Illinois | L | 73-50 |
| NCAAB | 2016/01/13 01:00 | Southern Illinois v Illinois St | W | 81-78 |
| NCAAB | 2015/02/26 01:00 | Illinois St v Southern Illinois | L | 73-56 |
| NCAAB | 2015/02/07 19:00 | Southern Illinois v Illinois St | W | 65-59 |
| NCAAB | 2014/03/01 12:00 | Southern Illinois v Illinois St | W | 66-65 |
| NCAAB | 2012/01/28 12:00 | Illinois St v Southern Illinois | L | 60-40 |
| NCAAB | 2012/01/01 12:00 | Southern Illinois v Illinois St | W | 86-71 |
| NCAAB | 2011/03/03 12:00 | Southern Illinois v Illinois St | W | 57-54 |
| NCAAB | 2011/01/23 12:00 | Illinois St v Southern Illinois | L | 59-55 |
| NCAAB | 2011/01/09 12:00 | Southern Illinois v Illinois St | W | 63-59 |
| NCAAB | 2010/01/23 12:00 | Southern Illinois v Illinois St | W | 81-80 |
| NCAAB | 2010/01/03 12:00 | Illinois St v Southern Illinois | L | 68-61 |
| NCAAB | 2009/02/04 12:00 | Southern Illinois v Illinois St | L | 57-60 |
| NCAAB | 2009/01/24 12:00 | Illinois St v Southern Illinois | L | 70-63 |
| NCAAB | 2008/03/01 12:00 | Southern Illinois v Illinois St | L | 49-57 |
| NCAAB | 2008/01/05 12:00 | Illinois St v Southern Illinois | L | 56-47 |
| NCAAB | 2007/01/27 12:00 | Southern Illinois v Illinois St | W | 73-62 |
| NCAAB | 2006/12/29 12:00 | Illinois St v Southern Illinois | W | 49-68 |
| NCAAB | 2006/01/28 12:00 | Illinois St v Southern Illinois | W | 52-65 |
| NCAAB | 2006/01/22 12:00 | Southern Illinois v Illinois St | W | 56-44 |
| NCAAB | 2005/02/16 12:00 | Illinois St v Southern Illinois | W | 59-66 |