[3] Penarol 3-2 Athletico Paranaense [1] 2020-10-21 00:30
Stadium: Estadio Campeon del Siglo Round: 6
Referee: Jose Mendez Home Manager: Mario Saralegui Away Manager: Eduardo Maciel de Barros
Head to Head
| Copa Libertadores | 2020/03/04 00:30 | Athletico Paranaense v Penarol | L | 1-0 |
| Copa Sudamericana | 2018/08/07 22:30 | Penarol v Athletico Paranaense | L | 1-4 |
| Copa Sudamericana | 2018/07/26 22:30 | Athletico Paranaense v Penarol | L | 2-0 |