[12] Leyton Orient 2-0 Southend [23] 2020-12-29 19:00
Stadium: Matchroom Stadium Round: 21
Referee: Craig Hicks Home Manager: Ross Embleton Away Manager: Mark Molesley
Head to Head
| England EFL Trophy | 2019/09/03 18:45 | Leyton Orient v Southend | W | 2-0 |
| Club Friendly List | 2018/07/28 14:00 | Leyton Orient v Southend | D | 2-2 |
| England EFL Trophy | 2016/10/04 18:45 | Southend v Leyton Orient | L | 1-0 |
| Club Friendly List | 2015/08/02 12:00 | Southend v Leyton Orient | W | 0-1 |