[107] Florida State 16-48 Louisville [68] 2020-10-24 16:00
Stadium: L&N Federal Credit Union Stadium Round: 1
Head to Head
| NCAAF | 2019/09/21 19:30 | Louisville v Florida State | W | 24-35 |
| NCAAF | 2018/09/29 19:30 | Florida State v Louisville | W | 28-24 |
| NCAAF | 2017/10/21 16:00 | Florida State v Louisville | L | 28-31 |
| NCAAF | 2017/10/21 16:00 | Louisville v Florida State | L | 31-28 |
| NCAAF | 2016/09/17 16:00 | Florida State v Louisville | L | 20-63 |
| NCAAF | 2015/10/17 16:00 | Florida State v Louisville | W | 41-21 |
| NCAAF | 2014/10/30 23:30 | Louisville v Florida State | W | 31-42 |
| NCAAF | 2002/09/26 12:00 | Louisville v Florida State | L | 26-20 |
| NCAAF | 2000/09/23 12:00 | Florida State v Louisville | W | 31-0 |