[8] Clemson 45-10 Virginia Tech [79] 2020-12-06 00:30
Stadium: Lane Stadium Round: 1
Head to Head
| NCAAF | 2017/10/01 00:19 | Clemson v Virginia Tech | W | 31-17 |
| NCAAF | 2017/10/01 00:00 | Virginia Tech v Clemson | W | 17-31 |
| NCAAF | 2016/12/04 01:00 | Virginia Tech v Clemson | W | 35-42 |
| NCAAF | 2012/10/20 12:00 | Clemson v Virginia Tech | W | 38-17 |
| NCAAF | 2011/12/03 12:00 | Clemson v Virginia Tech | W | 38-10 |
| NCAAF | 2011/10/01 12:00 | Virginia Tech v Clemson | W | 3-23 |
| NCAAF | 2007/10/06 12:00 | Clemson v Virginia Tech | L | 23-41 |
| NCAAF | 2006/10/26 12:00 | Virginia Tech v Clemson | L | 24-7 |
| NCAAF Bowl Games | 2001/01/01 12:00 | Clemson v Virginia Tech | L | 20-41 |