[1] Gremio 2-0 Guarani Asuncion [2] 2020-12-04 00:30
Stadium: Arena do Gremio Round: 4
Referee: Wilmar Alexander Roldan Perez Home Manager: Renato Gaucho Away Manager: Gustavo Costas
Head to Head
| Copa Libertadores Qualification | 2020/11/27 00:30 | Guarani Asuncion v Gremio | W | 0-2 |
| Copa Libertadores | 2017/04/28 00:45 | Gremio v Guarani Asuncion | W | 4-1 |
| Copa Libertadores | 2017/04/20 22:30 | Guarani Asuncion v Gremio | D | 1-1 |