[11] PIT Penguins 3-0 BUF Sabres [31] 2021-03-14 00:00
Stadium: KeyBank Center
Home Manager: Ralph Krueger Away Manager: Mike Sullivan
Head to Head
| NHL | 2021/03/12 00:00 | PIT Penguins v BUF Sabres | W | 5-2 |
| NHL | 2020/03/06 00:00 | PIT Penguins v BUF Sabres | W | 4-2 |
| NHL | 2020/02/22 18:00 | BUF Sabres v PIT Penguins | L | 5-2 |
| NHL | 2019/10/03 23:00 | BUF Sabres v PIT Penguins | L | 3-1 |
| NHL Pre-Season | 2019/09/28 20:00 | BUF Sabres v PIT Penguins | L | 3-2 |
| NHL Pre-Season | 2019/09/16 23:00 | PIT Penguins v BUF Sabres | L | 4-5 |
| NHL | 2019/03/14 23:00 | PIT Penguins v BUF Sabres | W | 5-0 |
| NHL | 2019/03/02 00:00 | PIT Penguins v BUF Sabres | L | 3-4 |
| NHL | 2018/11/20 00:00 | BUF Sabres v PIT Penguins | L | 5-4 |
| NHL Pre-Season | 2018/09/26 23:00 | BUF Sabres v PIT Penguins | W | 1-5 |
| NHL Pre-Season | 2018/09/18 23:00 | PIT Penguins v BUF Sabres | L | 2-3 |
| NHL | 2017/12/03 00:00 | BUF Sabres v PIT Penguins | W | 1-5 |
| NHL | 2017/12/02 00:00 | PIT Penguins v BUF Sabres | W | 4-0 |
| NHL | 2017/11/15 00:00 | BUF Sabres v PIT Penguins | W | 4-5 |
| NHL Pre-Season | 2017/09/27 23:00 | BUF Sabres v PIT Penguins | W | 4-5 |
| NHL Pre-Season | 2017/09/19 23:00 | PIT Penguins v BUF Sabres | L | 3-4 |
| NHL | 2017/03/21 23:00 | PIT Penguins v BUF Sabres | W | 3-1 |
| NHL | 2017/03/05 22:00 | BUF Sabres v PIT Penguins | W | 3-4 |
| NHL | 2016/11/20 00:00 | PIT Penguins v BUF Sabres | L | 1-2 |