[8] America de Cali 2-0 Deportes Tolima [4] 2021-04-18 20:30
Stadium: Olimpico Pascual Guerrero Round: 19
Referee: Wilmar Alexander Roldan Perez Home Manager: Juan Cruz Real Away Manager: Hernan Torres
Head to Head
| Colombia Primera A | 2020/09/27 01:10 | Deportes Tolima v America de Cali | L | 1-0 |
| Colombia Primera A | 2019/07/21 00:45 | Deportes Tolima v America de Cali | W | 0-1 |
| Colombia Primera A | 2019/02/01 01:00 | America de Cali v Deportes Tolima | W | 3-1 |
| Colombia Primera A | 2018/07/29 00:45 | Deportes Tolima v America de Cali | L | 1-0 |
| Colombia Primera A | 2018/02/10 23:00 | America de Cali v Deportes Tolima | D | 1-1 |
| Colombia Primera A | 2017/07/16 00:45 | America de Cali v Deportes Tolima | W | 3-0 |
| Colombia Primera A | 2017/02/08 01:00 | Deportes Tolima v America de Cali | L | 2-1 |