[7] Guayaquil SC 2-0 LDU Portoviejo [9] 2021-09-15 00:00
Stadium: Estadio Modelo Alberto Spencer Herrera Round: 32
Head to Head
| Ecuador LigaPro Serie B | 2021/07/22 20:00 | LDU Portoviejo v Buhos ULVR | L | 2-0 |
| Ecuador LigaPro Serie B | 2021/06/26 23:00 | Buhos ULVR v LDU Portoviejo | W | 2-1 |
| Ecuador LigaPro Serie B | 2021/03/18 00:00 | LDU Portoviejo v Buhos ULVR | W | 1-3 |