[17] Santiago Wanderers 0-3 Melipilla [11] 2021-05-08 22:00
Stadium: Estadio Elias Figueroa Brander Round: 7
Referee: Francisco Gilabert Home Manager: Ronald Hugo Fuentes Nunez Away Manager: John Sebastian Armijo
Head to Head
| Chile Primera B | 2019/07/29 23:30 | Melipilla v Santiago Wanderers | L | 2-1 |
| Chile Primera B | 2019/05/04 20:30 | Santiago Wanderers v Melipilla | W | 2-1 |
| Chile Primera B | 2018/08/26 18:00 | Santiago Wanderers v Melipilla | W | 1-0 |
| Chile Primera B | 2018/06/06 20:00 | Melipilla v Santiago Wanderers | L | 2-1 |