[34] Louisiana Tech 34-35 Mississippi State [34] 2021-09-04 20:00
Stadium: Davis Wade Stadium at Scott Field Round: 1
Home Manager: Mike Leach Away Manager: Skip Holtz
Head to Head
| NCAAF | 2018/11/03 23:30 | Louisiana Tech v Mississippi State | L | 3-45 |
| NCAAF | 2017/09/09 23:30 | Louisiana Tech v Mississippi State | L | 21-57 |
| NCAAF | 2015/10/17 16:00 | Mississippi State v Louisiana Tech | L | 45-20 |
| NCAAF | 2011/09/24 12:00 | Mississippi State v Louisiana Tech | L | 26-20 |
| NCAAF | 2008/08/30 12:00 | Louisiana Tech v Mississippi State | W | 22-14 |