[17] Santiago Wanderers 0-4 Colo Colo [9] 2021-07-29 19:00
Stadium: Estadio Elias Figueroa Brander Round: 13
Referee: Felipe Gonzalez Home Manager: Emiliano Astorga Away Manager: Gustavo Quinteros
Head to Head
| Chile Primera Division | 2021/01/06 13:30 | Santiago Wanderers v Colo Colo | W | 3-0 |
| Chile Primera Division | 2020/08/29 17:30 | Colo Colo v Santiago Wanderers | W | 2-3 |
| Chile Super Cup | 2018/01/26 22:00 | Colo Colo v Santiago Wanderers | L | 3-0 |
| Chile Apertura | 2017/10/15 18:30 | Colo Colo v Santiago Wanderers | L | 2-0 |
| Chile Clausura | 2017/03/11 15:00 | Santiago Wanderers v Colo Colo | L | 0-2 |
| Chile Apertura | 2016/09/24 15:00 | Colo Colo v Santiago Wanderers | D | 1-1 |
| Chile Clausura | 2016/04/30 19:00 | Colo Colo v Santiago Wanderers | L | 2-1 |
| Chile Apertura | 2016/01/11 21:00 | Santiago Wanderers v Colo Colo | W | 2-1 |
| Chile Clausura | 2015/05/02 18:30 | Colo Colo v Santiago Wanderers | L | 3-1 |
| Chile Apertura | 2014/12/06 20:00 | Santiago Wanderers v Colo Colo | W | 2-0 |