Head to Head
| South America - World Cup Qualifying | 2020/10/13 21:00 | Ecuador v Uruguay | L | 4-2 |
| Copa America | 2019/06/16 22:00 | Uruguay v Ecuador | W | 4-0 |
| South America - World Cup Qualifying | 2016/11/10 23:00 | Uruguay v Ecuador | W | 2-1 |
| South America - World Cup Qualifying | 2015/11/12 21:00 | Ecuador v Uruguay | L | 2-1 |