[18] Unam Pumas 2-2 Santos Laguna [13] 2017-11-05 18:00
Weather: Good Stadium: Estadio Olimpico Universitario Pitch: Good Round: 16
Referee: Luis Enrique Santander Aguirre Home Manager: David Patino Oviedo Away Manager: Robert Siboldi
Head to Head
| Mexico Liga MX | 2017/03/05 18:00 | Unam Pumas v Santos Laguna | W | 2-1 |
| Mexico Liga MX | 2016/09/18 23:00 | Santos Laguna v Unam Pumas | L | 3-1 |
| Club Friendly List | 2016/07/02 23:00 | Unam Pumas v Santos Laguna | L | 1-2 |
| Mexico Liga MX | 2016/02/21 18:00 | Unam Pumas v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2015/08/29 02:30 | Santos Laguna v Unam Pumas | W | 3-4 |
| Mexico Liga MX | 2015/04/19 17:00 | Unam Pumas v Santos Laguna | W | 1-0 |
| Mexico Liga MX | 2014/10/25 02:30 | Santos Laguna v Unam Pumas | D | 1-1 |