[7] TEN Titans 34-31 IND Colts [21] 2021-10-31 17:00
Stadium: Lucas Oil Stadium Round: 1
Head to Head
| NFL | 2021/09/26 17:00 | IND Colts v TEN Titans | W | 16-25 |
| NFL | 2020/11/29 18:00 | TEN Titans v IND Colts | W | 45-26 |
| NFL | 2020/11/13 01:20 | IND Colts v TEN Titans | L | 34-17 |
| NFL | 2019/12/01 18:00 | TEN Titans v IND Colts | W | 31-17 |
| NFL | 2019/09/15 17:00 | IND Colts v TEN Titans | L | 19-17 |
| NFL | 2018/12/31 01:20 | IND Colts v TEN Titans | L | 33-17 |
| NFL | 2018/11/18 18:00 | TEN Titans v IND Colts | L | 10-38 |
| NFL | 2017/11/26 18:00 | TEN Titans v IND Colts | W | 20-16 |
| NFL | 2017/10/17 00:30 | IND Colts v TEN Titans | W | 22-36 |
| NFL | 2016/11/20 18:00 | TEN Titans v IND Colts | L | 17-24 |
| NFL | 2016/10/23 17:00 | IND Colts v TEN Titans | L | 34-26 |
| NFL | 2016/01/03 18:00 | IND Colts v TEN Titans | L | 30-24 |
| NFL | 2015/09/27 17:00 | TEN Titans v IND Colts | L | 33-35 |
| NFL | 2014/12/28 18:00 | TEN Titans v IND Colts | L | 10-27 |
| NFL | 2014/09/28 17:00 | IND Colts v TEN Titans | L | 41-17 |