[3] Club Deportes Santa Cruz 1-0 Deportes Temuco [7] 2021-09-14 19:30
Stadium: Estadio Municipal Joaquín Muñoz García Round: 20
Head to Head
| Chile Primera B | 2021/05/10 22:00 | Deportes Temuco v Club Deportes Santa Cruz | W | 0-1 |
| Chile Primera B | 2020/12/06 13:00 | Deportes Temuco v Club Deportes Santa Cruz | L | 2-1 |
| Chile Primera B | 2020/09/20 16:30 | Club Deportes Santa Cruz v Deportes Temuco | L | 0-2 |
| Chile Primera B | 2019/04/06 21:00 | Club Deportes Santa Cruz v Deportes Temuco | L | 0-4 |