[5] Club Deportes Santa Cruz 1-2 Deportes Copiapo [2] 2021-10-08 21:30
Stadium: Estadio Municipal Joaquín Muñoz García Round: 24
Head to Head
| Chile Primera B | 2021/06/07 16:00 | Deportes Copiapo v Club Deportes Santa Cruz | L | 2-0 |
| Chile Primera B | 2020/11/30 13:30 | Deportes Copiapo v Club Deportes Santa Cruz | L | 2-0 |
| Chile Primera B | 2020/10/12 16:30 | Club Deportes Santa Cruz v Deportes Copiapo | L | 1-4 |
| Chile Primera B | 2019/04/28 01:00 | Deportes Copiapo v Club Deportes Santa Cruz | L | 3-0 |