[5] Tranmere 0-2 Northampton [6] 2021-10-23 14:00
Stadium: Prenton Park Round: 14
Referee: Tom Nield Home Manager: Micky Mellon Away Manager: Jon Brady
Head to Head
| England League 2 | 2019/02/05 19:45 | Tranmere v Northampton | L | 1-2 |
| England League 2 | 2018/09/01 14:00 | Northampton v Tranmere | D | 1-1 |
| England League 2 | 2015/03/14 15:00 | Northampton v Tranmere | L | 1-0 |
| England League 2 | 2014/12/28 15:00 | Tranmere v Northampton | W | 2-1 |