[6] Hamburg 3-0 Karlsruher SC [9] 2022-04-16 18:30
Stadium: Volksparkstadion Round: 30
Referee: Patrick Alt Home Manager: Tim Walter Away Manager: Christian Eichner
Head to Head
| Germany DFB Pokal | 2022/03/02 17:30 | Hamburg v Karlsruher SC | D | 2-2 |
| Germany Bundesliga II | 2021/11/06 19:30 | Karlsruher SC v Hamburg | D | 1-1 |
| Germany Bundesliga II | 2021/04/29 16:30 | Hamburg v Karlsruher SC | D | 1-1 |
| Germany Bundesliga II | 2020/12/21 19:30 | Karlsruher SC v Hamburg | W | 1-2 |
| Germany Bundesliga II | 2020/02/08 12:00 | Hamburg v Karlsruher SC | W | 2-0 |
| Germany Bundesliga II | 2019/08/25 11:30 | Karlsruher SC v Hamburg | W | 2-4 |
| Germany Bundesliga Play-Offs | 2015/06/01 17:00 | Karlsruher SC v Hamburg | W | 1-2 |
| Germany Bundesliga Play-Offs | 2015/05/28 18:30 | Hamburg v Karlsruher SC | D | 1-1 |
| Germany Bundesliga I | 1993/04/03 13:30 | Karlsruher SC v Hamburg | L | 1-0 |
| Germany Bundesliga I | 1992/09/18 18:00 | Hamburg v Karlsruher SC | L | 1-2 |