[26] Union Santa Fe 4-0 San Lorenzo [2] 2021-08-07 18:45
Stadium: Estadio 15 de Abril Round: 5
Referee: Dario Herrera Home Manager: Juan Manuel Azconzabal Away Manager: Leandro Romagnoli
Head to Head
| Argentina Superliga | 2019/08/31 18:30 | San Lorenzo v Union Santa Fe | L | 2-1 |
| Argentina Superliga | 2018/08/28 00:00 | Union Santa Fe v San Lorenzo | D | 1-1 |
| Argentina Superliga | 2018/03/03 20:00 | San Lorenzo v Union Santa Fe | D | 0-0 |
| Argentina Superliga | 2016/12/10 20:00 | San Lorenzo v Union Santa Fe | L | 3-2 |
| Argentina Liga Profesional | 2015/07/11 22:10 | Union Santa Fe v San Lorenzo | D | 1-1 |