[5] Athletic Bilbao 1-2 Rayo Vallecano [10] 2021-09-21 20:00
Stadium: San Mames Stadium Round: 6
Referee: Jose Luis Munuera Montero Home Manager: Marcelino Away Manager: Andoni Iraola
Head to Head
| Spain La Liga | 2019/04/14 12:00 | Athletic Bilbao v Rayo Vallecano | W | 3-2 |
| Spain La Liga | 2018/10/24 17:00 | Rayo Vallecano v Athletic Bilbao | D | 1-1 |
| Spain La Liga | 2016/04/10 18:30 | Athletic Bilbao v Rayo Vallecano | W | 1-0 |
| Spain La Liga | 2015/11/29 17:15 | Rayo Vallecano v Athletic Bilbao | W | 0-3 |
| Spain La Liga | 2015/02/22 16:00 | Athletic Bilbao v Rayo Vallecano | W | 1-0 |
| Spain La Liga | 2014/09/24 18:00 | Rayo Vallecano v Athletic Bilbao | L | 2-1 |