[16] Sevilla 3-0 Rayo Vallecano [14] 2021-08-15 20:15
Stadium: Ramon Sanchez Pizjuan Round: 1
Referee: Isidro Diaz de Mera Escuderos Home Manager: Julen Lopetegui Away Manager: Andoni Iraola
Head to Head
| Spain La Liga | 2019/04/25 17:30 | Sevilla v Rayo Vallecano | W | 5-0 |
| Spain La Liga | 2018/08/19 18:15 | Rayo Vallecano v Sevilla | W | 1-4 |
| Spain La Liga | 2016/02/21 11:00 | Rayo Vallecano v Sevilla | D | 2-2 |
| Spain La Liga | 2015/09/26 18:30 | Sevilla v Rayo Vallecano | W | 3-2 |
| Spain La Liga | 2015/04/26 17:00 | Sevilla v Rayo Vallecano | W | 2-0 |
| Spain La Liga | 2014/12/07 11:00 | Rayo Vallecano v Sevilla | W | 0-1 |