[14] Unam Pumas 1-3 Atletico San Luis [9] 2021-08-08 17:00
Stadium: Estadio Olimpico Universitario Round: 3
Referee: Oscar Macias Romo Home Manager: Andres Lillini Away Manager: Marcelo Mendez
Head to Head
| Mexico Liga MX | 2021/03/20 23:00 | Atletico San Luis v Unam Pumas | W | 0-1 |
| Mexico Liga MX | 2020/09/13 17:00 | Unam Pumas v Atletico San Luis | W | 3-0 |
| Mexico Liga MX | 2020/02/09 18:00 | Unam Pumas v Atletico San Luis | W | 4-0 |
| Mexico Cup | 2019/10/03 02:00 | Atletico San Luis v Unam Pumas | W | 0-4 |
| Mexico Cup | 2019/08/01 02:00 | Unam Pumas v Atletico San Luis | D | 1-1 |
| Mexico Liga MX | 2019/07/20 22:00 | Atletico San Luis v Unam Pumas | W | 0-2 |
| World Club Friendlies | 2018/07/08 00:03 | Atletico San Luis v Unam Pumas | L | 2-0 |