[12] Cruz Azul 0-2 Mazatlan FC [13] 2021-07-27 01:00
Stadium: Estadio Azteca Round: 1
Referee: Diego Montano Robles Home Manager: Juan Reynoso Away Manager: Benat San Jose
Head to Head
| Mexico Liga MX | 2021/03/04 03:00 | Cruz Azul v Mazatlan FC | W | 1-0 |
| Mexico Liga MX | 2020/09/19 02:30 | Mazatlan FC v Cruz Azul | W | 2-3 |
| Mexico Liga MX | 2016/01/10 02:30 | Mazatlan FC v Cruz Azul | D | 2-2 |
| Mexico Liga MX | 2015/07/25 22:00 | Cruz Azul v Mazatlan FC | L | 0-3 |
| Mexico Liga MX | 2015/04/18 00:30 | Mazatlan FC v Cruz Azul | L | 2-0 |
| Mexico Liga MX | 2014/10/25 22:00 | Cruz Azul v Mazatlan FC | W | 3-1 |