[7] Leon 0-0 Atletico San Luis [6] 2021-10-02 22:00
Stadium: Estadio Leon Round: 12
Referee: Victor Alfonso Caceres Hernandez Home Manager: Ariel Holan Away Manager: Marcelo Mendez
Head to Head
| Mexico Liga MX | 2021/02/02 03:00 | Leon v Atletico San Luis | W | 3-1 |
| Mexico Liga MX | 2020/09/27 22:00 | Atletico San Luis v Leon | W | 0-2 |
| Mexico Liga MX | 2020/02/15 01:00 | Atletico San Luis v Leon | L | 3-1 |
| Mexico Liga MX | 2019/10/27 00:00 | Leon v Atletico San Luis | W | 3-2 |
| Mexico Cup | 2015/08/06 00:00 | Leon v Atletico San Luis | D | 3-3 |
| Mexico Cup | 2015/07/29 00:00 | Atletico San Luis v Leon | W | 1-2 |