[13] Southampton 0-0 West Ham [2] 2021-09-11 14:00
Stadium: St. Mary's Stadium Round: 4
Referee: David Coote Home Manager: Ralph Hasenhuttl Away Manager: David Moyes
Head to Head
| England Premier League | 2021/05/23 15:00 | West Ham v Southampton | L | 3-0 |
| England Premier League | 2020/12/29 18:00 | Southampton v West Ham | D | 0-0 |
| England Premier League | 2020/02/29 15:00 | West Ham v Southampton | L | 3-1 |
| England Premier League | 2019/12/14 17:30 | Southampton v West Ham | L | 0-1 |
| England Premier League | 2019/05/04 14:00 | West Ham v Southampton | L | 3-0 |
| England Premier League | 2018/12/27 19:45 | Southampton v West Ham | L | 1-2 |
| England Premier League | 2018/03/31 14:00 | West Ham v Southampton | L | 3-0 |
| England Premier League | 2017/08/19 14:00 | Southampton v West Ham | W | 3-2 |
| England Premier League | 2017/02/04 15:00 | Southampton v West Ham | L | 1-3 |
| England Premier League | 2016/09/25 15:00 | West Ham v Southampton | W | 0-3 |
| England Premier League | 2016/02/06 17:30 | Southampton v West Ham | W | 1-0 |
| England Premier League | 2015/12/28 17:30 | West Ham v Southampton | L | 2-1 |
| England Premier League | 2015/02/11 19:45 | Southampton v West Ham | D | 0-0 |
| England Premier League | 2014/08/30 14:00 | West Ham v Southampton | W | 1-3 |