[6] Man Utd 1-1 Southampton [10] 2022-02-12 12:30
Stadium: Old Trafford Round: 25
Referee: Stuart Attwell Home Manager: Ralf Rangnick Away Manager: Ralph Hasenhuttl
Head to Head
| England Premier League | 2021/08/22 13:00 | Southampton v Man Utd | D | 1-1 |
| England Premier League | 2021/02/02 20:15 | Man Utd v Southampton | W | 9-0 |
| England Premier League | 2020/11/29 14:00 | Southampton v Man Utd | W | 2-3 |
| England Premier League | 2020/07/13 19:00 | Man Utd v Southampton | D | 2-2 |
| England Premier League | 2019/08/31 11:30 | Southampton v Man Utd | D | 1-1 |
| England Premier League | 2019/03/02 15:00 | Man Utd v Southampton | W | 3-2 |
| England Premier League | 2018/12/01 17:30 | Southampton v Man Utd | D | 2-2 |
| England Premier League | 2017/12/30 17:30 | Man Utd v Southampton | D | 0-0 |
| England Premier League | 2017/09/23 14:00 | Southampton v Man Utd | W | 0-1 |
| England Premier League | 2017/05/17 18:45 | Southampton v Man Utd | D | 0-0 |
| England EFL Cup | 2017/02/26 16:30 | Man Utd v Southampton | W | 3-2 |
| England Premier League | 2016/08/19 19:00 | Man Utd v Southampton | W | 2-0 |
| England Premier League | 2016/01/23 15:00 | Man Utd v Southampton | L | 0-1 |
| England Premier League | 2015/09/20 15:00 | Southampton v Man Utd | W | 2-3 |
| England Premier League | 2015/01/11 16:00 | Man Utd v Southampton | L | 0-1 |
| England Premier League | 2014/12/08 20:00 | Southampton v Man Utd | W | 1-2 |