[10] Southampton 2-0 Everton [16] 2022-02-19 15:00
Stadium: St. Mary's Stadium Round: 26
Referee: Andrew Madley Home Manager: Ralph Hasenhuttl Away Manager: Frank Lampard
Head to Head
| England Premier League | 2021/08/14 14:00 | Everton v Southampton | L | 3-1 |
| England Premier League | 2021/03/01 20:00 | Everton v Southampton | L | 1-0 |
| England Premier League | 2020/10/25 14:00 | Southampton v Everton | W | 2-0 |
| England Premier League | 2020/07/09 17:00 | Everton v Southampton | D | 1-1 |
| England Premier League | 2019/11/09 15:00 | Southampton v Everton | L | 1-2 |
| England Premier League | 2019/01/19 15:00 | Southampton v Everton | W | 2-1 |
| England EFL Cup | 2018/10/02 18:45 | Everton v Southampton | W | 4-5 |
| England Premier League | 2018/08/18 14:00 | Everton v Southampton | L | 2-1 |
| England Premier League | 2018/05/05 16:30 | Everton v Southampton | D | 1-1 |
| England Premier League | 2017/11/26 13:30 | Southampton v Everton | W | 4-1 |
| England Premier League | 2017/01/02 15:00 | Everton v Southampton | L | 3-0 |
| England Premier League | 2016/11/27 16:30 | Southampton v Everton | W | 1-0 |
| England Premier League | 2016/04/16 14:00 | Everton v Southampton | D | 1-1 |
| England Premier League | 2015/08/15 11:45 | Southampton v Everton | L | 0-3 |
| England Premier League | 2015/04/04 14:00 | Everton v Southampton | L | 1-0 |
| England Premier League | 2014/12/20 15:00 | Southampton v Everton | W | 3-0 |