[6] Deportivo Pereira 3-0 Once Caldas [18] 2021-10-16 23:05
Stadium: Estadio Hernan Ramirez Villegas Round: 14
Referee: Diego Leon Escalante Guiterrez Home Manager: Alexis Marquez Away Manager: Eduardo Lara Lozano
Head to Head
| Colombia Primera A | 2021/08/16 01:10 | Once Caldas v Deportivo Pereira | W | 0-1 |
| Colombia Primera A | 2021/03/01 23:00 | Deportivo Pereira v Once Caldas | W | 2-0 |
| Colombia Primera A | 2020/10/06 21:00 | Once Caldas v Deportivo Pereira | W | 0-3 |
| Colombia Primera A | 2020/03/02 01:15 | Deportivo Pereira v Once Caldas | L | 1-3 |
| World Club Friendlies | 2020/01/12 20:30 | Once Caldas v Deportivo Pereira | W | 0-1 |
| World Club Friendlies | 2018/07/14 01:00 | Deportivo Pereira v Once Caldas | W | 1-0 |
| Club Friendly List | 2015/07/05 20:30 | Deportivo Pereira v Once Caldas | L | 0-3 |
| Colombia Cup | 2014/08/07 21:00 | Deportivo Pereira v Once Caldas | W | 2-1 |
| Colombia Cup | 2014/07/03 00:00 | Once Caldas v Deportivo Pereira | L | 5-2 |