[8] Universidad Guadalajara 1-0 Tlaxcala FC [15] 2021-10-27 22:00
Stadium: Estadio Jalisco Round: 14
Head to Head
| Mexico Liga de Expansion | 2021/01/17 23:00 | Universidad Guadalajara v Tlaxcala FC | D | 1-1 |
| Mexico Liga de Expansion | 2020/09/15 21:00 | Tlaxcala FC v Universidad Guadalajara | W | 1-3 |