[16] Melipilla 1-1 Santiago Wanderers [17] 2021-10-04 21:30
Stadium: Estadio Municipal de La Pintana Round: 24
Referee: Cristian Garay Home Manager: Rodrigo Cordova Away Manager: Emiliano Astorga
Head to Head
| Chile Primera Division | 2021/05/08 22:00 | Santiago Wanderers v Melipilla | W | 0-3 |
| Chile Primera B | 2019/07/29 23:30 | Melipilla v Santiago Wanderers | W | 2-1 |
| Chile Primera B | 2019/05/04 20:30 | Santiago Wanderers v Melipilla | L | 2-1 |
| Chile Primera B | 2018/08/26 18:00 | Santiago Wanderers v Melipilla | L | 1-0 |
| Chile Primera B | 2018/06/06 20:00 | Melipilla v Santiago Wanderers | W | 2-1 |