[6] CD Antofagasta 0-0 La Serena [12] 2021-11-08 21:00
Stadium: Regional de Antofagasta Round: 31
Referee: Matias Quila Home Manager: Diego Reveco Away Manager: Ivo Basay
Head to Head
| Chile Primera Division | 2021/08/02 18:30 | La Serena v CD Antofagasta | D | 1-1 |
| Chile Primera Division | 2021/01/11 20:00 | CD Antofagasta v La Serena | D | 2-2 |
| Chile Primera Division | 2020/02/03 22:30 | La Serena v CD Antofagasta | W | 0-1 |