[4] Penarol 1-0 Club Atletico Progreso [15] 2021-08-14 22:00
Stadium: Estadio Campeon del Siglo Round: 14
Referee: Leodan Frankin Gonzalez Cabrera Home Manager: Mauricio Larriera Away Manager: Maximiliano Viera Dutra
Head to Head
| Uruguay Clausura | 2021/03/25 19:00 | Club Atletico Progreso v Penarol | W | 0-2 |
| Uruguay Apertura | 2020/10/06 21:00 | Penarol v Club Atletico Progreso | W | 2-1 |
| Uruguay Clausura | 2019/11/27 20:00 | Club Atletico Progreso v Penarol | D | 0-0 |
| Uruguay Torneo Intermedio | 2019/07/20 18:00 | Club Atletico Progreso v Penarol | D | 1-1 |
| Uruguay Apertura | 2019/05/26 21:00 | Penarol v Club Atletico Progreso | D | 2-2 |
| Uruguay Clausura | 2018/10/27 21:30 | Penarol v Club Atletico Progreso | W | 1-0 |
| Uruguay Torneo Intermedio | 2018/05/12 18:30 | Club Atletico Progreso v Penarol | L | 4-3 |
| Uruguay Apertura | 2018/04/29 18:30 | Club Atletico Progreso v Penarol | W | 0-1 |