Northwestern 14-47 Illinois 2021-11-27 20:30
Stadium: Memorial Stadium (Champaign, IL) Round: 1
Home Manager: Bret Bielema Away Manager: Pat Fitzgerald
Head to Head
| NCAAF | 2020/12/12 17:00 | Illinois v Northwestern | W | 10-28 |
| NCAAF | 2019/11/30 17:00 | Northwestern v Illinois | W | 29-10 |
| NCAAF | 2018/11/24 20:30 | Illinois v Northwestern | W | 16-24 |
| NCAAF | 2017/11/25 21:00 | Northwestern v Illinois | W | 42-7 |
| NCAAF | 2016/11/26 17:00 | Illinois v Northwestern | W | 21-42 |
| NCAAF | 2015/11/28 20:30 | Illinois v Northwestern | W | 14-24 |
| NCAAF | 2014/11/29 17:00 | Northwestern v Illinois | L | 33-47 |
| NCAAF | 2012/11/24 12:00 | Northwestern v Illinois | W | 50-14 |
| NCAAF | 2011/10/01 12:00 | Illinois v Northwestern | L | 38-35 |
| NCAAF | 2010/11/20 12:00 | Northwestern v Illinois | L | 27-48 |
| NCAAF | 2009/11/14 12:00 | Illinois v Northwestern | W | 16-21 |
| NCAAF | 2008/11/22 12:00 | Northwestern v Illinois | W | 27-10 |
| NCAAF | 2007/11/17 12:00 | Illinois v Northwestern | L | 41-22 |
| NCAAF | 2006/11/18 12:00 | Northwestern v Illinois | W | 27-16 |
| NCAAF | 2005/11/19 12:00 | Illinois v Northwestern | W | 21-38 |
| NCAAF | 2004/11/20 12:00 | Northwestern v Illinois | W | 28-21 |
| NCAAF | 2003/11/22 12:00 | Illinois v Northwestern | W | 20-37 |
| NCAAF | 2002/11/23 12:00 | Northwestern v Illinois | L | 24-31 |
| NCAAF | 2001/11/22 12:00 | Illinois v Northwestern | L | 34-28 |
| NCAAF | 2000/11/18 12:00 | Northwestern v Illinois | W | 61-23 |