[49] Syracuse 30-33 Florida State [125] 2021-10-02 19:30
Stadium: Bobby Bowden Field at Doak Campbell Stadium Round: 1
Home Manager: Mike Norvell Away Manager: Dino Babers
Head to Head
| NCAAF | 2019/10/26 19:30 | Syracuse v Florida State | L | 17-35 |
| NCAAF | 2018/09/15 16:00 | Florida State v Syracuse | W | 7-30 |
| NCAAF | 2017/11/04 16:20 | Syracuse v Florida State | L | 24-27 |
| NCAAF | 2016/11/19 20:30 | Florida State v Syracuse | L | 45-14 |
| NCAAF | 2015/10/31 16:00 | Florida State v Syracuse | L | 45-21 |
| NCAAF | 2014/10/11 16:00 | Syracuse v Florida State | L | 20-38 |
| NCAAF | 2005/10/01 12:00 | Florida State v Syracuse | L | 38-14 |
| NCAAF | 2004/10/09 12:00 | Syracuse v Florida State | L | 13-17 |