[69] Virginia 34-33 Louisville [59] 2021-10-09 19:00
Stadium: L&N Federal Credit Union Stadium Round: 1
Home Manager: Scott Satterfield Away Manager: Bronco Mendenhall
Head to Head
| NCAAF | 2020/11/14 20:30 | Louisville v Virginia | W | 17-31 |
| NCAAF | 2019/10/26 19:30 | Virginia v Louisville | L | 21-28 |
| NCAAF | 2018/09/22 16:30 | Louisville v Virginia | W | 3-27 |
| NCAAF | 2017/11/11 20:30 | Virginia v Louisville | L | 21-38 |
| NCAAF | 2016/10/29 16:00 | Louisville v Virginia | L | 32-25 |
| NCAAF | 2015/11/14 17:30 | Louisville v Virginia | L | 38-31 |
| NCAAF | 2014/09/13 16:30 | Virginia v Louisville | W | 23-21 |