Penarol 1-2 Athletico Paranaense 2021-09-24 00:30
Stadium: Estadio Campeon del Siglo Round: 2
Referee: Diego Mirko Haro Sueldo Home Manager: Mauricio Larriera Away Manager: Paulo Autuori de Mello
Head to Head
| Copa Libertadores | 2020/10/21 00:30 | Penarol v Athletico Paranaense | W | 3-2 |
| Copa Libertadores | 2020/03/04 00:30 | Athletico Paranaense v Penarol | L | 1-0 |
| Copa Sudamericana | 2018/08/07 22:30 | Penarol v Athletico Paranaense | L | 1-4 |
| Copa Sudamericana | 2018/07/26 22:30 | Athletico Paranaense v Penarol | L | 2-0 |