Extremadura 0-6 UD San Sebastian Reyes 2022-02-04 20:00
Stadium: Estadio Francisco de la Hera Round: 22
Head to Head
| Spain Primera Division RFEF Group 1 | 2021/08/29 17:30 | UD San Sebastian Reyes v Extremadura | L | 1-0 |
| Spain Segunda B Group 5 | 2021/05/02 10:00 | UD San Sebastian Reyes v Extremadura | L | 3-0 |
| Spain Segunda B Group 5 | 2021/04/11 16:00 | Extremadura v UD San Sebastian Reyes | D | 0-0 |