[8] TSG Hoffenheim 2-4 Bayer Leverkusen [3] 2022-05-07 13:30
Stadium: Rhein-Neckar-Arena Round: 33
Referee: Frank Willenborg Home Manager: Sebastian Hoeness Away Manager: Gerardo Seoane
Head to Head
| Germany Bundesliga I | 2021/12/15 19:30 | Bayer Leverkusen v TSG Hoffenheim | D | 2-2 |
| Germany Bundesliga I | 2021/04/12 18:30 | TSG Hoffenheim v Bayer Leverkusen | D | 0-0 |
| Germany Bundesliga I | 2020/12/13 17:00 | Bayer Leverkusen v TSG Hoffenheim | L | 4-1 |
| Germany Bundesliga I | 2020/02/01 14:30 | TSG Hoffenheim v Bayer Leverkusen | W | 2-1 |
| Germany Bundesliga I | 2019/08/31 13:30 | Bayer Leverkusen v TSG Hoffenheim | D | 0-0 |
| Germany Bundesliga I | 2019/03/29 19:30 | TSG Hoffenheim v Bayer Leverkusen | W | 4-1 |
| Germany Bundesliga I | 2018/11/03 14:30 | Bayer Leverkusen v TSG Hoffenheim | W | 1-4 |
| Germany Bundesliga I | 2018/01/20 14:30 | TSG Hoffenheim v Bayer Leverkusen | L | 1-4 |
| Germany Bundesliga I | 2017/08/26 13:30 | Bayer Leverkusen v TSG Hoffenheim | D | 2-2 |
| Germany Bundesliga I | 2017/03/18 14:30 | TSG Hoffenheim v Bayer Leverkusen | W | 1-0 |
| Germany Bundesliga I | 2016/10/22 13:30 | Bayer Leverkusen v TSG Hoffenheim | W | 0-3 |
| Germany Bundesliga I | 2016/01/23 14:30 | TSG Hoffenheim v Bayer Leverkusen | D | 1-1 |
| Germany Bundesliga I | 2015/08/15 13:30 | Bayer Leverkusen v TSG Hoffenheim | L | 2-1 |
| Germany Bundesliga I | 2015/05/16 13:30 | Bayer Leverkusen v TSG Hoffenheim | L | 2-0 |
| Germany Bundesliga I | 2014/12/17 19:00 | TSG Hoffenheim v Bayer Leverkusen | L | 0-1 |