[4] Shakhtar Donetsk 0-5 Real Madrid [2] 2021-10-19 19:00
Stadium: Olimpiyskiy National Sports Complex Round: 3
Referee: Srdjan Jovanovic Home Manager: Roberto De Zerbi Away Manager: Carlo Ancelotti
Head to Head
| UEFA Champions League | 2020/12/01 17:55 | Shakhtar Donetsk v Real Madrid | W | 2-0 |
| UEFA Champions League | 2020/10/21 16:55 | Real Madrid v Shakhtar Donetsk | W | 2-3 |
| UEFA Champions League | 2015/11/25 19:45 | Shakhtar Donetsk v Real Madrid | L | 3-4 |
| UEFA Champions League | 2015/09/15 18:45 | Real Madrid v Shakhtar Donetsk | L | 4-0 |