[16] Leyton Orient 0-2 Salford City [10] 2022-02-12 15:00
Stadium: Matchroom Stadium Round: 32
Referee: Ben Speedie Home Manager: Kenneth Francis Jackett Away Manager: Gary Bowyer
Head to Head
| England League 2 | 2021/08/07 14:00 | Salford City v Leyton Orient | D | 1-1 |
| England League 2 | 2021/05/08 15:00 | Salford City v Leyton Orient | L | 3-0 |
| England League 2 | 2021/01/02 15:00 | Leyton Orient v Salford City | W | 1-0 |
| England League 2 | 2019/08/31 14:00 | Salford City v Leyton Orient | D | 1-1 |
| England National League | 2019/01/05 15:00 | Leyton Orient v Salford City | L | 0-3 |
| England National League | 2018/08/04 11:30 | Salford City v Leyton Orient | D | 1-1 |