Bayer Leverkusen 1-2 Karlsruher SC 2021-10-27 16:30
Stadium: BayArena Round: 8
Referee: Tobias Welz Home Manager: Gerardo Seoane Away Manager: Christian Eichner
Head to Head
| Germany DFB Pokal | 2017/08/11 18:45 | Karlsruher SC v Bayer Leverkusen | W | 0-3 |
| Germany Bundesliga I | 1993/03/27 14:30 | Karlsruher SC v Bayer Leverkusen | D | 1-1 |
| Germany Bundesliga I | 1992/09/05 13:30 | Bayer Leverkusen v Karlsruher SC | W | 5-1 |