[12] Ayacucho FC 1-3 Cienciano [6] 2021-10-22 18:15
Stadium: Estadio Ciudad de Cumaná Round: 16
Referee: Victor Hugo Carrillo Casanova Home Manager: Walter Fiori Away Manager: Gerardo Pablo Ameli
Head to Head
| Peru Liga 1 | 2021/04/23 23:00 | Ayacucho FC v Cienciano | D | 1-1 |
| Peru Liga 1 | 2020/02/29 20:30 | Cienciano v Ayacucho FC | W | 1-4 |
| Peru Liga 1 | 2015/11/15 18:00 | Cienciano v Ayacucho FC | D | 1-1 |
| Peru Liga 1 | 2015/07/15 18:30 | Ayacucho FC v Cienciano | D | 0-0 |
| Peru Liga 1 | 2014/09/21 16:00 | Cienciano v Ayacucho FC | D | 0-0 |
| Peru Liga 1 | 2014/06/21 18:15 | Ayacucho FC v Cienciano | W | 3-1 |