[2] STL Blues 2-4 DET Red Wings [4] 2021-11-25 00:30
Stadium: Little Caesars Arena
Home Manager: Jeff Blashill Away Manager: Craig Berube
Head to Head
| NHL | 2019/10/27 21:00 | STL Blues v DET Red Wings | W | 5-4 |
| NHL Pre-Season | 2019/09/26 23:00 | STL Blues v DET Red Wings | L | 1-4 |
| NHL | 2019/03/22 00:00 | DET Red Wings v STL Blues | W | 2-5 |
| NHL | 2018/11/29 00:00 | STL Blues v DET Red Wings | L | 3-4 |
| NHL | 2018/03/01 01:00 | DET Red Wings v STL Blues | W | 1-2 |
| NHL | 2017/12/09 18:00 | STL Blues v DET Red Wings | W | 6-1 |
| NHL | 2017/02/16 01:00 | STL Blues v DET Red Wings | W | 2-0 |
| NHL | 2016/10/28 00:00 | DET Red Wings v STL Blues | L | 2-1 |