[14] Brentford 3-0 Southampton [15] 2022-05-07 14:00
Stadium: Brentford Community Stadium Round: 36
Referee: Michael Salisbury Home Manager: Thomas Frank Away Manager: Ralph Hasenhuttl
Head to Head
| England Premier League | 2022/01/11 19:45 | Southampton v Brentford | L | 4-1 |
| England EFL Cup | 2020/09/16 18:45 | Southampton v Brentford | W | 0-2 |
| Elite Club Friendlies | 2017/07/22 14:00 | Brentford v Southampton | D | 2-2 |