2 de Mayo 1-8 Sportivo San Lorenzo 2021-10-26 18:30
Stadium: Estadio Monumental Rio Parapiti Round: 34
Head to Head
| Paraguay Division Intermedia | 2021/07/09 21:30 | Sportivo San Lorenzo v 2 de Mayo | L | 3-1 |
| Paraguay Division Intermedia | 2018/09/09 14:00 | Sportivo San Lorenzo v 2 de Mayo | L | 2-1 |
| Paraguay Division Intermedia | 2018/06/03 19:30 | 2 de Mayo v Sportivo San Lorenzo | W | 1-0 |