Stadium: CFSB Center
Home Manager: Matt McMahon Away Manager: Brian Barone
| NCAAB | 2022/01/08 21:00 | Murray State v SIU Edwardsville | L | 74-69 |
| NCAAB | 2021/02/21 01:30 | SIU Edwardsville v Murray State | L | 62-89 |
| NCAAB | 2021/02/15 22:00 | Murray State v SIU Edwardsville | L | 86-57 |
| NCAAB | 2020/02/22 20:00 | Murray State v SIU Edwardsville | L | 59-58 |
| NCAAB | 2020/02/02 01:00 | SIU Edwardsville v Murray State | L | 55-74 |
| NCAAB | 2019/02/10 01:00 | SIU Edwardsville v Murray State | L | 55-86 |
| NCAAB | 2019/01/20 01:00 | Murray State v SIU Edwardsville | L | 82-72 |
| NCAAB | 2018/02/10 19:00 | Murray State v SIU Edwardsville | L | 75-66 |
| NCAAB | 2017/12/31 01:00 | SIU Edwardsville v Murray State | L | 63-87 |
| NCAAB | 2017/02/17 00:00 | SIU Edwardsville v Murray State | L | 73-84 |
| NCAAB | 2017/01/15 01:00 | SIU Edwardsville v Murray State | L | 59-67 |
| NCAAB | 2016/02/12 01:00 | SIU Edwardsville v Murray State | L | 64-70 |
| NCAAB | 2016/01/24 01:00 | Murray State v SIU Edwardsville | L | 70-54 |
| NCAAB | 2015/02/13 01:00 | Murray State v SIU Edwardsville | L | 78-46 |
| NCAAB | 2015/01/25 01:00 | SIU Edwardsville v Murray State | L | 54-60 |
| NCAAB | 2012/01/21 12:00 | SIU Edwardsville v Murray State | L | 65-82 |
| NCAAB | 2011/01/26 12:00 | SIU Edwardsville v Murray State | L | 61-67 |
| NCAAB | 2010/01/27 12:00 | Murray State v SIU Edwardsville | L | 86-49 |
| NCAAB | 2009/12/30 12:00 | SIU Edwardsville v Murray State | L | 51-82 |
| NCAAB | 2004/11/20 12:00 | Murray State v SIU Edwardsville | L | 75-67 |
| NCAAB | 2003/11/26 12:00 | Murray State v SIU Edwardsville | L | 81-56 |
| NCAAB | 2002/11/25 12:00 | Murray State v SIU Edwardsville | L | 86-58 |