[12] Monterrey U20 1-2 Santos Laguna U20 [10] 2022-03-26 15:00
Stadium: Estadio BBVA Bancomer Round: 13
Head to Head
| Mexico U20 League | 2021/09/26 15:30 | Santos Laguna U20 v Monterrey U20 | L | 4-1 |
| Mexico U20 League | 2021/02/14 17:00 | Santos Laguna U20 v Monterrey U20 | W | 1-2 |
| Mexico U20 League | 2020/08/08 14:00 | Monterrey U20 v Santos Laguna U20 | W | 2-1 |
| Mexico U20 League | 2019/12/08 17:00 | Santos Laguna U20 v Monterrey U20 | L | 2-0 |
| Mexico U20 League | 2019/12/05 15:00 | Monterrey U20 v Santos Laguna U20 | L | 1-2 |
| Mexico U20 League | 2019/08/23 16:00 | Santos Laguna U20 v Monterrey U20 | L | 5-4 |
| Mexico U20 League | 2019/05/19 16:15 | Santos Laguna U20 v Monterrey U20 | D | 0-0 |
| Mexico U20 League | 2019/05/16 14:00 | Monterrey U20 v Santos Laguna U20 | W | 3-0 |
| Mexico U20 League | 2019/03/20 15:00 | Monterrey U20 v Santos Laguna U20 | W | 2-0 |
| Mexico U20 League | 2018/10/26 16:00 | Santos Laguna U20 v Monterrey U20 | W | 0-2 |
| Mexico U20 League | 2018/03/11 17:00 | Santos Laguna U20 v Monterrey U20 | L | 3-2 |
| Mexico U20 League | 2017/09/27 14:00 | Monterrey U20 v Santos Laguna U20 | L | 2-3 |
| Mexico U20 League | 2017/04/19 16:03 | Santos Laguna U20 v Monterrey U20 | D | 1-1 |